Stem Cell/ Bone Marrow Donation

Blaze · 06-25-2010, 05:51 PM

Thank you Spirit Dancer for posting this thread. I went to work this morning.

I talked with my CEO and she sent out a e-mail to everyone in our facility. I was so happy to see the response! We will be having a drive Tuesday. And at this very moment we have 64 people signed up to get there cheek swab, and yes, I had to explain to a few of our fellow employees that it's not the cheek that there originally thinking about

Finally our hospital has something to be excited about besides donating blood. Once again, what a wonderful Idea Spirit Dancer, now if I can get the other 39 associates to swab away!

Spirit Dancer · 06-25-2010, 06:28 PM

Quote:

Originally Posted by Blaze

Thank you Spirit Dancer for posting this thread. I went to work this morning.

I talked with my CEO and she sent out a e-mail to everyone in our facility. I was so happy to see the response! We will be having a drive Tuesday. And at this very moment we have 64 people signed up to get there cheek swab, and yes, I had to explain to a few of our fellow employees that it's not the cheek that there originally thinking about

Finally our hospital has something to be excited about besides donating blood. Once again, what a wonderful Idea Spirit Dancer, now if I can get the other 39 associates to swab away!

Blaze
Thank you and your co workers, such a wonderful gift
you all are giving.
Wishing now there were more drives for Bone Marrow and Stem Cell
what a great idea you had.

Blaze · 06-25-2010, 07:49 PM

Quote:

Originally Posted by Spirit Dancer

Blaze
Thank you and your co workers, such a wonderful gift
you all are giving.
Wishing now there were more drives for Bone Marrow and Stem Cell
what a great idea you had.

On the contrary my dear. It was your posting that got me thinking that it would be a wonderful drive to do. We all give blood. It was now time to get my hospital co-workers to step it up and give more. So. It is you, that should get the applause and thanks!

friskyfemme · 06-26-2010, 10:36 AM

I had plannd to do this a couple of years after a news article published about a local guy needing a bone marrow transplant. However, during my procrastination, the young man died. I will never know if I could have been a match. Still wears on me. I didn't know there was a registry. Thanks for bringing this to my awareness. And stem cell donation!?
How does that work with live donors? Did I miss that?

Spirit Dancer · 06-26-2010, 10:47 AM

Quote:

Originally Posted by friskyfemme

I had plannd to do this a couple of years after a news article published about a local guy needing a bone marrow transplant. However, during my procrastination, the young man died. I will never know if I could have been a match. Still wears on me. I didn't know there was a registry. Thanks for bringing this to my awareness. And stem cell donation!?
How does that work with live donors? Did I miss that?

Live Donor Liver Transplantation
Sander Florman1 and Charles M. Miller2
1Tulane University School of Medicine, Tulane University Hospital and Clinic, New Orleans, LA,
and 2The Cleveland Clinic Foundation, Cleveland, OH
Received January 10, 2005; accepted February 2, 2006.
With ever-increasing demand for liver replacement, supply of organs is the limiting factor and a significant number of patients
die while waiting. Live donor liver transplantation has emerged as an important option for many patients, particularly small
pediatric patients and those adults that are disadvantaged by the current deceased donor allocation system. Ideally there would
be no need to subject perfectly healthy people in the prime of their lives to a potentially life-threatening operation to procure
transplantable organs. Donor safety is imperative and cannot be compromised regardless of the implication for the intended
recipient. The evolution of split liver transplantation is the basis upon which live donor transplantation has become possible.
The live donor procedures are considerably more complex than whole organ decreased donor transplantation and there are
unique considerations involved in the assessment of any specific recipient and donor. Donor selection and evaluation have
become highly specialized. The critical issue of size matching is determined by both the actual size of the donor graft and the
recipient as well as the degree of recipient portal hypertension. The outcomes after live donor liver transplantation have been
at least comparable to those of deceased donor transplantation. Nevertheless, all efforts should be made to improve deceased
donor donation so as to minimize the need for live donors. Transplant physicians, particularly surgeons, must take
responsibility for regulating and overseeing these procedures. Liver Transpl 12:499-510, 2006. © 2006 AASLD.

Spirit Dancer · 06-26-2010, 10:49 AM

The demand for liver transplantation has continued to
increase in the last three decades and has far outpaced
the supply of organs from deceased donors. In the U.S.
alone, more than 90,000 people are on transplant waiting
lists, whereas the number of deceased liver donors
in recent years has remained stable at approximately
6,000.1 More than 18,000 patients are waiting
for livers. Allocation of these precious, life-saving organs
is currently dictated by patients’ scores on the
Model for End-stage Liver Disease, a disease-severity
index based solely on bilirubin, creatinine, and international
normalized ratio. The Model for End-stage
Liver Disease (or, in children, the Pediatric End-stage
Liver Disease model) allows prioritization of the sickest
patients.2,3 Still, death on the waiting list in 2004 was
greater than 10%.1
Faced with these statistics, physicians caring for
these patients have endeavored to perform transplants
with partial liver grafts from healthy, volunteer live donors.
An estimated 7,000 living donor liver transplants
have been performed worldwide.

Spirit Dancer · 06-26-2010, 10:52 AM

ADVANTAGES OF LIVE DONORS
Organs from living donors offer many potential advantages
over organs from brain-dead donors. The most important
advantages of live donation are that it optimizes
the timing of transplantation and frees patients from the
waiting list. These factors have become especially helpful
for patients who are disadvantaged by the cadaver organ
allocation scheme, including patients with tumors, cholestatic
diseases, or blood type O, as well as those who are
retransplantation candidates.
Preservation time is minimal in live donor transplants,
so there is significantly less ischemic damage to
the liver. Live donors are by definition healthy, and
therefore the quality of the donated liver is much better.
Brain death results in many adverse pathophysiologic
effects that damage the liver. Perhaps most importantly,
live donor transplantation increases the global
pool of transplantable organs, allowing more people to
benefit from this potentially life-saving therapy.
DISADVANTAGES OF LIVE DONORS
There are, however, a number of disadvantages to live
donor transplantation which must be considered carefully.
The donor, a perfectly healthy volunteer, faces
unequivocal risks of morbidity and even mortality
which put the procedure at odds with the very basic
tenets of medicine and the oath that all physicians
pledge to keep: Primum non nocere – First, cause no
harm. The risk of death for donors of a left lateral segment
or a left lobe is estimated to be approximately
0.1%, whereas the risk for donors of a right lobe is
estimated to be approximately 0.4 to 0.5%.25

friskyfemme · 06-26-2010, 11:02 AM

So 'live stem cell donor' is liver transplant? My sister has just been diagnosed with 'C'. She has started chemo therapy with a research drug (weekly injections and daily pill). If after six months the treatment looks as if it is working she will continue, otherwise, next year there is a new drug regiment being introduced, She will start on that one. If that doesn't show results in 6 months, then she will need the transplant. I was thinking I needed to wait to check for match on the liver. So I will go ahead and test for her match. Can one person do more that a one time 'live liver donation' after regrowing the liver?

Spirit Dancer · 06-26-2010, 11:12 AM

Quote:

Originally Posted by friskyfemme

So 'live stem cell donor' is liver transplant? My sister has just been diagnosed with 'C'. She has started chemo therapy with a research drug (weekly injections and daily pill). If after six months the treatment looks as if it is working she will continue, otherwise, next year there is a new drug regiment being introduced, She will start on that one. If that doesn't show results in 6 months, then she will need the transplant. I was thinking I needed to wait to check for match on the liver. So I will go ahead and test for her match. Can one person do more that a one time 'live liver donation' after regrowing the liver?

FF
The live donor part was for a partial liver transplant. Stem Cells are harvested the same way as a blood donation unless it is a bone marrow donation then it is a surgical procedure. I'm not sure if it would be wise to donate a partial liver more than once, I'll look into it, makes an interesting question. Will add your sister to the candle list if it is okay with you.

06-26-2010, 10:36 AM	#4
friskyfemme Member How Do You Identify?: femme Preferred Pronoun?: precious Relationship Status: down to earth Join Date: Nov 2009 Location: Arizona Posts: 332 My Photo Gallery Thanks: 395 Thanked 370 Times in 152 Posts Rep Power: 828	I had plannd to do this a couple of years after a news article published about a local guy needing a bone marrow transplant. However, during my procrastination, the young man died. I will never know if I could have been a match. Still wears on me. I didn't know there was a registry. Thanks for bringing this to my awareness. And stem cell donation!? How does that work with live donors? Did I miss that? __________________ Love and Light, FF

06-26-2010, 10:49 AM	#6
Spirit Dancer Senior Member How Do You Identify?: Complex but Tender Preferred Pronoun?: ~Ma`am~ Relationship Status: Shotgun Rider Join Date: Nov 2009 Location: Following the red road Posts: 4,519 My Photo Gallery Thanks: 9,304 Thanked 12,913 Times in 3,466 Posts Rep Power: 21474856	The demand for liver transplantation has continued to increase in the last three decades and has far outpaced the supply of organs from deceased donors. In the U.S. alone, more than 90,000 people are on transplant waiting lists, whereas the number of deceased liver donors in recent years has remained stable at approximately 6,000.1 More than 18,000 patients are waiting for livers. Allocation of these precious, life-saving organs is currently dictated by patients’ scores on the Model for End-stage Liver Disease, a disease-severity index based solely on bilirubin, creatinine, and international normalized ratio. The Model for End-stage Liver Disease (or, in children, the Pediatric End-stage Liver Disease model) allows prioritization of the sickest patients.2,3 Still, death on the waiting list in 2004 was greater than 10%.1 Faced with these statistics, physicians caring for these patients have endeavored to perform transplants with partial liver grafts from healthy, volunteer live donors. An estimated 7,000 living donor liver transplants have been performed worldwide. __________________ “For it was not into my ear you whispered, but into my heart. It was not my lips you kissed, but my soul.” Judy Garland

06-26-2010, 10:52 AM	#7
Spirit Dancer Senior Member How Do You Identify?: Complex but Tender Preferred Pronoun?: ~Ma`am~ Relationship Status: Shotgun Rider Join Date: Nov 2009 Location: Following the red road Posts: 4,519 My Photo Gallery Thanks: 9,304 Thanked 12,913 Times in 3,466 Posts Rep Power: 21474856	ADVANTAGES OF LIVE DONORS Organs from living donors offer many potential advantages over organs from brain-dead donors. The most important advantages of live donation are that it optimizes the timing of transplantation and frees patients from the waiting list. These factors have become especially helpful for patients who are disadvantaged by the cadaver organ allocation scheme, including patients with tumors, cholestatic diseases, or blood type O, as well as those who are retransplantation candidates. Preservation time is minimal in live donor transplants, so there is significantly less ischemic damage to the liver. Live donors are by definition healthy, and therefore the quality of the donated liver is much better. Brain death results in many adverse pathophysiologic effects that damage the liver. Perhaps most importantly, live donor transplantation increases the global pool of transplantable organs, allowing more people to benefit from this potentially life-saving therapy. DISADVANTAGES OF LIVE DONORS There are, however, a number of disadvantages to live donor transplantation which must be considered carefully. The donor, a perfectly healthy volunteer, faces unequivocal risks of morbidity and even mortality which put the procedure at odds with the very basic tenets of medicine and the oath that all physicians pledge to keep: Primum non nocere – First, cause no harm. The risk of death for donors of a left lateral segment or a left lobe is estimated to be approximately 0.1%, whereas the risk for donors of a right lobe is estimated to be approximately 0.4 to 0.5%.25 __________________ “For it was not into my ear you whispered, but into my heart. It was not my lips you kissed, but my soul.” Judy Garland

06-26-2010, 11:02 AM	#8
friskyfemme Member How Do You Identify?: femme Preferred Pronoun?: precious Relationship Status: down to earth Join Date: Nov 2009 Location: Arizona Posts: 332 My Photo Gallery Thanks: 395 Thanked 370 Times in 152 Posts Rep Power: 828	So 'live stem cell donor' is liver transplant? My sister has just been diagnosed with 'C'. She has started chemo therapy with a research drug (weekly injections and daily pill). If after six months the treatment looks as if it is working she will continue, otherwise, next year there is a new drug regiment being introduced, She will start on that one. If that doesn't show results in 6 months, then she will need the transplant. I was thinking I needed to wait to check for match on the liver. So I will go ahead and test for her match. Can one person do more that a one time 'live liver donation' after regrowing the liver? __________________ Love and Light, FF

06-25-2010, 05:51 PM	#1
Blaze Senior Member How Do You Identify?: With my drivers Lic. Preferred Pronoun?: Gentleman.. Depends on the Situation. Relationship Status: Last Rodeo, what a ride, many sunrises & sunsets to be had... Join Date: Nov 2009 Location: where a realtor had me sign the dotted line Posts: 1,901 My Photo Gallery Thanks: 6,466 Thanked 5,457 Times in 1,450 Posts Rep Power: 21474853	Thank you Spirit Dancer for posting this thread. I went to work this morning. I talked with my CEO and she sent out a e-mail to everyone in our facility. I was so happy to see the response! We will be having a drive Tuesday. And at this very moment we have 64 people signed up to get there cheek swab, and yes, I had to explain to a few of our fellow employees that it's not the cheek that there originally thinking about Finally our hospital has something to be excited about besides donating blood. Once again, what a wonderful Idea Spirit Dancer, now if I can get the other 39 associates to swab away!